The BRAINS group of Prof. Deniz Kirik at the University of Lund is looking for a highly motivated post-doctoral fellow. Our research focus lies on understanding the mechanisms leading to the selective neurodegeneration observed in Parkinson’s disease patients. The BRAINS group contributes to this task with its expertise in studies utilizing animal models of human diseases. The advertised project aims to elucidate the relation between oxidative stress and the neurodegenerative process in a novel transgenic mouse model of Parkinson’s disease. Furthermore, we plan to identify specific pathways or markers, which are crucial in modulating cell death in Parkinson´s disease and can therefore be used to develop neuroprotective therapies.
-Highly qualified candidates with a clear commitment to basic neuroscience research and documented expertise in transgenic mouse models are invited to apply. -The outstanding applicant should have at least 3 years experience with genetic mouse models of neurodegenerative diseases, including stereotaxic surgeries, behavioral tests and histological analysis. -He / she must have expert level knowledge and documented experience in unbiased stereological quantification of cell numbers. -Advanced level knowledge and expertise with in vivo microdialysis and analytical techniques such as HPLC and mass spectrometry (LC-MS/MS) analysis is a must requirement. -Candidates with knowhow in use of viral vectors for applications in the brain will be preferred. Applicants will hold a PhD in neuroscience or related disciplines and should be fluent in English, as documented with publications in international journals.