A researcher is wanted to work on the project entitled ‘Development of nanobeads enclosing drugs that kill fish tuberculosis mycobacteria in a zebrafish model’ funded by the Norwegian Research Council’s FriMedBio program. At theUniversityofOslothe selected person will work in the polymer chemistry group of Prof. Bo Nyström at the Department of Chemistry, who is actively collaborating with Prof. Gareth Griffiths (Department of Molecular Biosciences). The goal is to develop new therapeutic strategies using biodegradable polymeric nanoparticles enclosing drugs and anti-microbial peptides against Mycobacterium tuberculosis. This is done using a model system, the fish tuberculosis organism M.marinum infecting the zebrafish. The main advantage of this vertebrate system is that both the nanoparticles and the bacteria can be seen directly in the live fish using fluorescence microscopy.
Applicants must hold a PhD degree in chemistry and minimum 2 years of postdoctoral work. Preference will be given for a candidate with a strong background in the synthesis and characterization of polymeric nanoparticles, ideally with experience in advanced characterization techniques (imaging and scattering techniques) and administration of drugs. It is also an advantage to have experience with microbiology, immunology, and/or pharmacy.